A personalized mRNA-based cancer vaccine has shown promise in extending life span. Merck and Moderna announced the success of this vaccine in a large, late-stage trial. The trial involved high-risk patients with melanoma.

The vaccine's success was announced on Wednesday, marking a significant development in cancer treatment. Further details about the trial and its outcomes are available from the source.

More information can be found from Merck and Moderna's announcement, which provides insight into the vaccine's potential in treating melanoma.